Obstela 5mg

Obeticholic acid (OCA) is a synthetic bile acid derivative that exhibits potent agonistic activity at the farnesoid X receptor (FXR), a nuclear receptor involved in the regulation of bile acid synthesis, transport, and metabolism. One of the primary benefits of OCA is its therapeutic potential in the management of various liver diseases, particularly non-alcoholic steatohepatitis (NASH). By activating FXR, OCA helps regulate lipid and glucose metabolism, reduce hepatic inflammation, and improve liver fibrosis, ultimately leading to the attenuation of NASH-related liver damage. Additionally, OCA has been studied for its potential in treating primary biliary cholangitis (PBC), a chronic autoimmune liver disease characterized by progressive destruction of the bile ducts. By modulating bile acid homeostasis, OCA can improve liver function and delay disease progression in patients with PBC.