Motilium 10mg

Domperidone, a dopamine receptor antagonist, offers a variety of benefits and features primarily in the management of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease (GERD). By antagonizing dopamine receptors in the gastrointestinal tract, particularly in the stomach and proximal small intestine, Domperidone enhances gastrointestinal motility and accelerates gastric emptying. This prokinetic action helps alleviate symptoms such as nausea, vomiting, bloating, and delayed gastric emptying associated with gastroparesis, a condition characterized by impaired stomach emptying and gastrointestinal dysmotility. Additionally, Domperidone’s antiemetic effects further contribute to symptom relief by reducing the frequency and severity of nausea and vomiting in patients with gastrointestinal disorders or those undergoing chemotherapy.

Moreover, Domperidone’s ability to increase lower esophageal sphincter tone and improve esophageal peristalsis makes it an effective treatment option for GERD, a common condition characterized by acid reflux and heartburn. By promoting proper esophageal clearance and reducing the frequency of reflux episodes, Domperidone helps alleviate symptoms and prevent complications such as esophagitis and Barrett’s esophagus. Furthermore, Domperidone crosses the blood-brain barrier to a lesser extent than other dopamine receptor antagonists, minimizing the risk of central nervous system side effects such as extrapyramidal symptoms and sedation. This favorable safety profile, combined with its efficacy in enhancing gastrointestinal motility and reducing reflux symptoms, makes Domperidone a valuable therapeutic agent for patients with various gastrointestinal disorders, offering symptom relief and improving overall quality of life.